HomeHealth NewsA mutation linked to ALS and dementia miswires gene expression

A mutation linked to ALS and dementia miswires gene expression

August 13, 2025

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C9 aberrant splicing in patient-derived MNs. Credit: Nature Neuroscience (2025). DOI: 10.1038/s41593-025-02039-5

It may be time to rethink certain genetic mutations associated with two devastating neurodegenerative disorders—amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)—according to a new Nature Neuroscience…

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