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SARS-CoV-2 spike protein accumulation linked to long-lasting brain effects

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Visualization of SARS-CoV-2 viral tropism in whole mouse bodies and SARS-CoV-2 spike protein persistency in skull marrow and brain. (A–E) SARS-CoV-2-GFP aerosol infection in K18-hACE2 mice. (A) Illustration of SARS-CoV-2-GFP infection and imaging of whole mouse body. (B) 3D reconstruction of whole mouse body showing localization of virus-encoded GFP and viral…

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