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Optogenetics approach reveals how alcohol use disorder impairs cognitive flexibility

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Excessive alcohol intake reduces thalamically evoked burst-pause response in DMS CINs and impairs reversal of operant conditioning. Credit: Science Advances (2024). DOI: 10.1126/sciadv.adn2446

Alcohol use disorder (AUD) affects about 400 million people worldwide and is a leading cause of serious illnesses such as cancer, cardiovascular…

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