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Stressful childhood experiences can accelerate brain aging

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Three-dimensional (3D) surface plots showing results of GAM analysis revealing significant nonlinear interaction effects among ACE scores, age, and (A) predicted log-transformed serum GFAP concentrations (p = 0.012) and (B) predicted log-transformed serum NfL concentrations (p Annals of Neurology (2025). DOI: 10.1002/ana.27161

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