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Enzyme-resistant glycan glue ameliorates spinal disk degeneration in animal models

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Design of a glycan glue for the damaged ECM of the NP tissue under IDD. Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-58946-5

As the world’s population ages, intervertebral disk degeneration (IDD) has become a major medical issue, causing chronic lower back pain and mobility issues that diminish the quality of life…

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