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Human-specific DNA enhancer linked to brain development and neuron proliferation

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Correlation analysis of resting state activity of each individual mouse. Credit: Nature (2025). DOI: 10.1038/s41586-025-09002-1

Duke University Medical Center-led research has identified a human-specific DNA enhancer that regulates neural progenitor proliferation and cortical size. Small genetic changes in HARE5 amplify a key developmental pathway,…

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