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HomeHealth NewsChromatin organization linked to p53 tumor suppression mechanism

Chromatin organization linked to p53 tumor suppression mechanism

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Cover art showing the nucleosome being bound by various cofactors and p53. Credit: Colby R. Sandate (EPFL)

Each cell in our bodies carries about two meters of DNA in its nucleus, packed into a tiny volume of just a few hundred cubic micrometers—about a millionth of a milliliter. The cell manages this by winding the strings of DNA around protein spools. The protein-DNA complexes are called…

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