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How lymphoma rewires the human genome

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Engineered mantle cell lymphoma cells. Credit: Roser Zaurin/Centro de Regulación Genómica

Translocations are chromosomal “cut and paste” errors that drive many lymphomas, a type of blood cancer and the sixth most common form of cancer overall. This includes mantle cell lymphoma, a rare but aggressive subtype diagnosed in about one in every 100,000 people each year.

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