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Human hippocampal neurogenesis shows unique gene expression patterns compared to other mammals

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Cross-species analysis of immature neurons in the hippocampus. Leveraging machine-learning-augmented scRNA-seq analysis, the team identified imGCs with transcriptome-wide immature neuronal characteristics in different mammals. They then performed cross-species comparisons of imGCs and mature granule cells (mGCs) from humans, monkeys, pigs and mice. Credits: Yi Zhou, Guo-li Ming, and Hongjun Song.

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