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An unexpected connection to lipid metabolism

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Images of immune synapses formed by NK-92 cells. Red: cytotoxic/lytic granules; Green: sphingolipids, GM1 or GB3; Cyan: Actin staining. Credit: Artem Kalinichenko

When immune cells strike, precision is everything. New research reveals how natural killer and T cells orchestrate the release of toxic granules—microscopic packages that destroy virus-infected or cancerous cells.

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