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Study reveals how uterine contractions are regulated by stretch and pressure during childbirth

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PIEZO1 transcripts in human uterine muscle at term. Green indicates smooth muscle fibers in the uterus, red marks PIEZO1 mRNA, and blue shows cell nuclei. Credit: Scripps Research

When labor begins, the uterus must coordinate rhythmic, well-timed contractions to deliver the baby safely. While hormones such as progesterone and oxytocin are key contributors to that process, scientists have long…

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