HomeHealth NewsMacrophage-killing bacterial toxin weakens the gut's defenses against ulcerative colitis

Macrophage-killing bacterial toxin weakens the gut’s defenses against ulcerative colitis

November 22, 2025

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An Aeromonas variant, MTB, promotes susceptibility to ulcerative colitis (UC) by disrupting colonic macrophages. Credit: Science (2025). DOI: 10.1126/science.adz4712

Ulcerative colitis (UC) is one of the most common inflammatory bowel diseases, a lifelong condition that can cause chronic inflammation and ulcers in the lining of the large intestine….

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Macrophage-killing bacterial toxin weakens the gut’s defenses against ulcerative colitis

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