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Circular single-stranded DNA molecules for safer genetic medicine

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Kano Therapeutics makes circular single stranded DNA (cssDNA) of custom lengths and sequences to improve genetic medicines. Pictured are Kano’s vials containing custom genetic constructs for an in vivo CAR-T study. Credit: Courtesy of Kano Therapeutics

To our immune system, a potentially lifesaving gene therapy can look a lot like a dangerous infection. That’s because most genetic medicine uses…

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