Mouse model reveals how muscular dystrophy triggers gut muscle over-contraction

Myotonic dystrophy type 1 (DM1) is the most common form of adult-onset muscular dystrophy, affecting about 1 in 8,000 people. While it is well known for causing muscle weakness and stiffness, DM1 also affects other organs, including the brain, heart and gastrointestinal (GI) tract. Although around 80% of people with DM1 experience GI problems that greatly…