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PRISM reanalyzes 4,400 tumors, reshaping the debate over tumor microbiomes

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Credit: Cancer Cell (2026). DOI: 10.1016/j.ccell.2026.01.007

When scientists sequence tumor DNA, they typically find small amounts of genetic code from bacteria, viruses and fungi—microorganisms that—if actually present in tumor tissues—could influence how they grow, evade immunity or respond to treatment. But do microorganisms truly…

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