HomeHealth NewsSurprising culprit leads to chronic rejection of transplanted lungs and hearts

Surprising culprit leads to chronic rejection of transplanted lungs and hearts

February 26, 2026

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A new study from researchers at WashU Medicine has identified lymphatic vessels and their cargo—a sugar molecule called hyaluronan (shown in pink)—as critical drivers of chronic rejection in transplanted lungs and hearts. A lung transplanted between genetically identical mice is laden with scar tissue full of hyaluronan (top half of image). Following a treatment to promote growth of lymphatic vessels, hyaluronan…

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Surprising culprit leads to chronic rejection of transplanted lungs and hearts

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