HomeHealth NewsBile acid and steroid signatures tied to extreme longevity

Bile acid and steroid signatures tied to extreme longevity

March 31, 2026

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A feedback loop linking healthy aging to NAD metabolism, gut microbiome activity, renal function, and oxidative stress. Markers of increased NAD synthesis and/or reduced inflammation (tryptophan/kynurenine), a healthy gut bacterial metabolism (aspartate/quinolinate, ergothioneine/TMAO), and reduced oxidative stress (methionine/methionine sulfoxide) are negatively…

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