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Inside tumors, immune cells hide a split personality—and one side could quietly decide cancer’s fate

April 22, 2026

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Ccl2 expression by IMs is critical for the recruitment of recMacs. Credit: Nature Immunology (2026). DOI: 10.1038/s41590-026-02445-2

Macrophages, key regulators of tissue health and immune defense, are among the most abundant immune cells in solid tumors. Their role in cancer has been difficult to define because even closely related…

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