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Longevity-linked APOE2 gene variant helps neurons repair DNA and resist aging

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This image is an artistic representation of how APOE2 promotes resilience to cellular senescence maintaining the integrity of DNA and the nuclear envelope. We show a neuron protected by APOE2 represented as orange dots across the cell, with a blue mesh representing the resistance to senescence. We highlight in golden the integrity of the nucleus and the protected genome. Credit: Ella Maru for the Buck Institute
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