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COPA mutations reveal alternative trigger for small intestine tumors

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The results of this study point to mutations in the COPA gene as an important driver of cancer progression in small intestinal adenomas. Credit: Professor Shigeki Sekine and Professor Toshiro Sato, Keio University School of Medicine, Japan

A signaling system known as the Wnt pathway plays a central role in how cells in the intestine grow, divide and renew themselves. Decades of research have…

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