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Fibronectin pathway may drive Marfan aortic damage, opening new drug targets

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Fibronectin accumulation in MFS aortas mediates aortic dilation. Credit: Nature Communications (2026). DOI: 10.1038/s41467-026-74707-4

A new study published in Nature Communications identifies a molecular signaling pathway that contributes to the development of life-threatening aortic aneurysms and dissections in Marfan syndrome, a…

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