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3D lifespan map suggests mouse ovaries keep a constant share of eggs primed

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A whole mouse ovary, made transparent and imaged in three dimensions. Each bright sphere is one of the roughly 5,000 egg cells a mouse is born with and will ever have. Larger ones are already growing while the smaller specks lie dormant, awaiting their turn across the reproductive lifespan. Credit: Arturo D’Angelo/Centro de Regulación Genómica

As mice age, their total egg reserve collapses…

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