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Youth-associated protein helps restore healthy function in immune cells in the aging brain

August 15, 2026

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Image reconstruction of microglia from an aged mouse treated with TIMP2 showing synaptic material (purple) within the cell’s lysosomes (green). Credit: Mount Sinai Health System

Researchers at the Icahn School of Medicine at Mount Sinai have identified a role for the youth-associated protein TIMP2 in supporting the healthy function of microglia, the brain’s resident immune cells.

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Youth-associated protein helps restore healthy function in immune cells in the aging brain

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Youth-associated protein helps restore healthy function in immune cells in the aging brain

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