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Research elucidates the mechanism behind frontotemporal lobar degeneration

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Alterations in the morphology of mushroom bodies in VCP/TER94 knockdown flies were rescued by the coexpression of wild-type VCP/TER94, but to a lesser extent by the coexpression of disease-associated mutant VCP/TER94. Credit: Dr. Masaaki Sone

Researchers have uncovered the mechanism underlying frontotemporal lobar degeneration (FTLD) caused by variants in the valosin-containing protein (VCP)…

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