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Holographic optogenetics could enable faster brain mapping for new discoveries

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High-speed synaptic connectivity mapping using holographic optogenetics and compressed sensing. Left: Experimental setup for probing synaptic connectivity and analyzing patterns of synaptic transmission. Right: An example map of synaptic connectivity from L2/3 of mouse V1. (Green neuron: postsynaptic pyramidal neuron held under patch-clamp; red: possible presynaptic neurons probed using…

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